Package: phase1RMD
Version: 1.0.9
Date: 2020-03-08
Title: Repeated Measurement Design for Phase I Clinical Trial
Author: Jun Yin, Yu Du, Sumithra Mandrekar
Maintainer: Jun Yin <vivien.jyin@gmail.com>
Depends: R (>= 3.0.0), coda, boot, rjags, mvtnorm, ggplot2
Suggests: BiocParallel
Imports: arrayhelpers
Description: Implements our Bayesian phase I repeated measurement
        design that accounts for multidimensional toxicity endpoints
        from multiple treatment cycles. The package also provides a
        novel design to account for both multidimensional toxicity
        endpoints and early-stage efficacy endpoints in the phase I
        design. For both designs, functions are provided to recommend
        the next dosage selection based on the data collected in the
        available patient cohorts and to simulate trial characteristics
        given design parameters. Yin, Jun, et al. (2017)
        <doi:10.1002/sim.7134>.
License: GPL (>= 2)
NeedsCompilation: no
LazyData: true
Packaged: 2026-07-04 07:01:56 UTC; root
Config/pak/sysreqs: jags
Repository: https://vivienjyin.r-universe.dev
Date/Publication: 2021-07-03 01:03:17 UTC
RemoteUrl: https://github.com/vivienjyin/phase1rmd
RemoteRef: HEAD
RemoteSha: af32af2e325c455e1531d52da4f96be12fb7d8df